Bullous Pemphigoid

Overview

Bullous pemphigoid (BP) is a rare autoimmune disorder that affects the skin and mucous membranes. The condition occurs when the body's immune system mistakenly attacks proteins in the skin that help to bind the outer and inner layers of skin together. This leads to the formation of fluid-filled blisters or bullae on the skin that can be painful and itchy. BP can affect people of all ages, but is most common in older adults. Treatment typically involves topical or oral steroids to reduce inflammation and suppress the immune system. Other medications, such as immunosuppressants or biologic therapies, may also be used in more severe cases. Proper wound care and skin protection are also important components of managing BP.